Home advantage and seven clean sheets indicate Junior are likeliest to edge a tight semi-final at Estadio Metropolitano; two previews list them as favourites.
Pick: Junior Barranquilla to Win to 1.7 @ Casumo - Up to £30 Free Bet for New Players*
Santa Fe's 115 shots on target this season show attacking quality while Junior have scored 35; combined these figures support both teams finding the net despite a cautious opening.
Pick: BTTS - Yes to 2.1 @ Casumo - Up to £30 Free Bet for New Players*
Santa Fe's superior shot volume creates genuine upset potential on the counter; this is a high-risk pick aligning with markets that pay well for an away victory.
Pick: Independiente Santa Fe to Win to 6.5 @ Casumo - Up to £30 Free Bet for New Players*
Draw no bet balances Junior's home control and defensive solidity with Santa Fe's attacking threat, offering protection if the match goes to a tight draw.
Pick: Draw No Bet - Junior Barranquilla to 1.85 @ Casumo - Up to £30 Free Bet for New Players*